QUESTION 5 Now consider the case of the blinking crustacean chip…

  

QUESTION 5 Now consider the case of the blinking crustacean chip…   QUESTION 5 Now consider the case of the blinking crustacean chip where the membrane potential goes from -50mV at rest to + 10mV on blink. You want to understand the ionic basis of these changes. You hypothesize that the change in membrane potential is caused by the opening of “mixed” Na-K channels.Your knowledge of the field of electrophysiology and your skills allow you to vary the membrane potential of the cell (ie depolarize or hyperpolarize the membrane in order to adjust the “resting” potential of the cell) by injecting current through a microelectrode. Suppose the EK is -90mV and the ENa is + 50mV.If your hypothesis is correct, indicate whether the statements are true (T) or false (F)? (6 points)   _____ If you set the membrane potential to + 10mV, the conductance of the flashing channels will be “0”._____ If the mixed Na-K channels are also permeable to Na + and K + ions, and if you set the quiescent membrane potential to -55mV, opening the mixed Na-K channels during blinking would have no effect on the membrane potential._____ If you set the membrane potential to -90mV by injecting negative current into the cell, opening the mixed Na-K channels when blinking would have no effect on the membrane potential._____ If you set the membrane potential to + 70mV by injecting positive current into the cell, there will be membrane potential depolarizations associated with the opening of these mixed Na-K channels when blinking._____ If you set the membrane potential to -100mV, opening these mixed Na-K channels when blinking would result in depolarizations of the membrane potential._____ Transport in these canals would be considered as “anti-port” co-transport. Biology Science Physiology BIO 2535

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