A lipophilic drug with a pK = 5.0 is taken orally and dissolves in the gastric environment of the stomach (pH = 1.0). What is the degree of

  

A lipophilic drug with a pK = 5.0 is taken orally and dissolves inthe gastric environment of the stomach (pH = 1.0). What is the degree of ionization of the drug in the stomach and the blood plasma (pH = 7.4)? In what direction will this drug tend to passively diffuse between the two compartments? Explain your answer in 50 words or less. Biology Science Pharmacology BIOL 4344

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